.pmrf-wrap{font-family:Inter,system-ui,-apple-system,Segoe UI,Arial;color:#15202b}
.pmrf-title h2{margin:0 0 5px;font-size:28px}
.pmrf-title p{margin:0 0 16px;color:#657483}
.pmrf-card{background:#fff;border:1px solid #d8e1e8;border-radius:14px;padding:18px;margin-bottom:16px}
.pmrf-grid{display:grid;grid-template-columns:2fr 1fr 1fr 1fr;gap:12px;align-items:end}
.pmrf-wrap label{display:block;font-size:12px;font-weight:750;color:#425463;margin-bottom:5px}
.pmrf-wrap input,.pmrf-wrap select{width:100%;height:44px;border:1px solid #aebbc6;border-radius:8px;padding:0 11px;font-size:16px;background:#fff;color:#15202b}
.pmrf-actions{display:flex;gap:10px;margin-top:13px;flex-wrap:wrap}
.pmrf-wrap button{height:44px;border:0;border-radius:8px;padding:0 18px;font-size:15px;font-weight:800;cursor:pointer}
.pmrf-primary{background:#1769aa;color:#fff}.pmrf-secondary{background:#e8eef3;color:#15202b}
.pmrf-alert{background:#fff6dc;border:1px solid #ecd58f;border-radius:10px;padding:12px;font-size:13px;color:#5f4800;margin-bottom:16px}
.pmrf-summary{display:flex;justify-content:space-between;gap:12px;align-items:center;flex-wrap:wrap}
.pmrf-summary strong{font-size:17px}.pmrf-query-display{margin-top:5px;color:#657483;font-size:13px}
.pmrf-pill{display:inline-block;padding:4px 8px;border-radius:999px;background:#eaf2f8;color:#315a75;font-size:11px;font-weight:800}
.pmrf-paper{padding:18px 0;border-bottom:1px solid #e5eaee}.pmrf-paper:last-child{border-bottom:0}
.pmrf-paper h3{font-size:19px;line-height:1.3;margin:0 0 7px}.pmrf-paper h3 a{color:#144f7b;text-decoration:none}.pmrf-paper h3 a:hover{text-decoration:underline}
.pmrf-meta{font-size:13px;color:#657483;line-height:1.45;margin-bottom:9px}
.pmrf-abstract{font-size:14px;line-height:1.55;color:#283640;white-space:pre-line}
.pmrf-abstract.collapsed{display:-webkit-box;-webkit-line-clamp:4;-webkit-box-orient:vertical;overflow:hidden}
.pmrf-paper-actions{display:flex;gap:8px;margin-top:10px;flex-wrap:wrap}
.pmrf-smallbtn,.pmrf-pubmedlink{display:inline-flex;align-items:center;justify-content:center;min-height:34px;padding:6px 10px;border-radius:7px;font-size:12px;font-weight:750;text-decoration:none;border:0;cursor:pointer}
.pmrf-smallbtn{background:#edf2f5;color:#334957}.pmrf-pubmedlink{background:#e4f3eb;color:#116443}
.pmrf-message{text-align:center;color:#6c7a86}.pmrf-footer-note{font-size:12px;color:#667783;line-height:1.5}
@media(max-width:820px){.pmrf-grid{grid-template-columns:1fr 1fr}.pmrf-keywords{grid-column:1/-1}}
@media(max-width:520px){.pmrf-grid{grid-template-columns:1fr}.pmrf-keywords{grid-column:auto}.pmrf-actions button{width:100%}}